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H5N1 Avian Influenza (Bird Flu)


Contents:
-General Information
-Transmission of H5N1 Virus, Avian Flu
-Symptoms for Humans
-Vaccines and Treatments for Humans
-What is UMDNJ doing to prepare for an influenza outbreak?
-What is New Jersey doing to prepare for an influenza outbreak?
-US Government's Role
-Additional Resources & Links


General Information

There are many strains of avian influenza; the one of primary concern is the influenza A virus referred to as H5N1. This virus is highly contagious in birds and is frequently fatal to them. The H5N1 virus does not usually infect humans but as of May 19, 2006, the World Health Organization has confirmed a total of 217 cases in humans with 123 deaths. For the most current cumulative case numbers, please visit the
World Health Organization (WHO).

At this time, the virus is not believed to be easily transmissible from human to human. However, once humans contract the virus from birds, there is the potential for the virus to mutate and spread through human contact. If this occurs, a human influenza pandemic could occur.

Transmission of H5N1 Virus, Avian Flu

In birds influenza is primarily an infection of the intestines, however, in a severe infection, the virus can be found throughout the body. The virus is transmitted from infected birds to healthy birds through nasal secretions, saliva, and feces. To date H5N1 is responsible for the deaths of over 25 million birds. Humans can become infected with the H5N1 virus through contact with infected poultry, surfaces infected by secretions/feces, direct contact with secretions/feces, or handling infected carcasses.

Symptoms for Humans

Symptoms are similar to that of seasonal influenza and include cough, fever, muscle aches, and sore throat. Infection can also lead to serious complications including eye infections, pneumonia, other respiratory conditions and death.

Vaccines and Treatments for Humans

There is currently no human vaccine available but progress has been made in its development in hopes that one will be readily available before a pandemic strikes.

There is some indication that theH5N1 virus may be resistant to amantadine and rimantidine, the two antivirals commonly used against influenza. However, at this time, more thorough studies are underway to determine the effectiveness of oseltamavir (Tamiflu ®) and zanamavir (Relenza™).

What is UMDNJ doing to prepare for an influenza outbreak?

Former UMDNJ President John J. Petillo established a university-wide task force whose focus is to prepare UMDNJ to respond effectively to an influenza pandemic as well as to seasonal flu outbreaks. Dr. Audrey R. Gotsch, Dean of UMDNJ-School of Public Health, chairs the task force, which is comprised of faculty and senior administrators throughout the UMDNJ system. Working in concert with officials from the New Jersey Department of Health and Senior Services and the U.S. Centers for Disease Control and Prevention, the task force will lead the development of plans and specific actions to protect the University's patients, faculty, staff and students in the event of an influenza pandemic or seasonal outbreak. The group will also share knowledge, experience and lessons learned from these efforts with healthcare providers, community organization, and others to help them make similar preparations.

What is New Jersey doing to prepare for an influenza outbreak?

For i nformation on the state of preparedness in New Jersey, pandemic planning information and a copy of the New Jersey Pandemic Influenza Plan, please visit http://www.nj.gov/health/er/avianflu.shtml.

The United States Government's Role

On November 1, 2005, President Bush announced the National Strategy for Pandemic Influenza and requested $7.1 billion in order to start implementing the strategy. Please visit pandemicflu.gov for more information on the state of readiness of the country and a copy of the National Strategy.

Additional Resources & Links
Click Here to view "Highly Pathogenic Avian Influenza: Ecology, Pathology, and Public Health:" A presentation by Dr. Jeanne Fair. (requires MS Explorer & Media Player).
Pandemicflu.gov
CDC- The Center for Disease Control and Protection
WHO- The World Health Organization
NJDHSS- New Jersey Department of Health and Senior Services
OSHA Guidance for Protecting Workers
Vaccination Information from NJDHSS
US HSS- The United States Department of Health and Human Services Pandemic Influenza Plan
H5N1 Avian Influenza: Most Recent Developments and Actions –
Updates by USAID Health
An in-depth look at the Bird Flu by BBC News

CNN's Special Report on the Bird Flu
Interactive map by BBC News


 

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HIGHLIGHTS


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